林滿玉

合聘教授

02-2871-2121 ext.2688 、02-28267000 ext.7983

myalin@nycu.edu.tw

氧化壓力和神經退化、藥物引起神經病變

學歷

年度學校名稱學位
1992美國科羅拉多州州立大學藥理學博士
1984臺灣大學藥理學碩士
1982臺灣大學藥學士

經歷

年度服務機關名稱單位職務
2016-迄今國立陽明大學藥學系系主任
2015-2016國立陽明大學藥學系籌備處主任
2008-2014國立陽明大學藥理學研究所所長
2008-迄今國立陽明大學藥理學研究所專任教授
2005-迄今榮民總醫院教學研究部合聘研究員
2005-2008國立陽明大學生理學研究所專任教授
2004-2005榮民總醫院教學研究部專任研究員
1998-2005國立陽明大學生理學研究所兼任副教授
1996-2004榮民總醫院教學研究部專任副研究員
1993-1996中央研究院生物醫學科學研究所博士後研究員
1992-1993美國國家衛生研究院客座博士後研究員

代表著作

排序編號著作名稱
1Anti-inflammatory effect of afatinib (an EGFR-TKI) on OGD-induced neuroinflammation. Chen YJ, Hsu CC, Shiao YJ, Wang HT, Lo YL, Lin AMY. Sci Rep. 2019 Feb 21;9(1):2516
2Soluble Epoxide Hydrolase Inhibition Attenuates MPTP-Induced Neurotoxicity in the Nigrostriatal Dopaminergic System: Involvement of alpha-Synuclein Aggregation and ER Stress.Huang HJ, Wang YT, Lin HC, Lee YH, Lin AMY. Mol Neurobiol. 2018 Jan; 55(1):138-144.
3Neuroprotective Effects of Baicalein on Acrolein-induced Neurotoxicity in the Nigrostriatal Dopaminergic System of Rat Brain. Zhao WZ, Wang HT, Huang HJ, Lo YL, Lin AMY. Mol Neurobiol. 2018 Jan;55(1):130-137.
4MicroRNA-224 down-regulates Glycine N-methyltransferase gene expression in Hepatocellular Carcinoma. Hung JH, Li CH, Yeh CH, Huang PC, Fang CC, Chen YF, Lee KJ, Chou CH, Cheng HY, Huang HD, Chen M, Tsai TF, Lin AMY, Yen CH, Tsou AP, Tyan YC, Chen YA.Sci Rep. 2018 Aug 16;8(1):12284.
5Acrolein acts as a neurotoxin in the nigrostriatal dopaminergic system of rat: involvement of α-synuclein aggregation and programmed cell death. Wang YT, Lin HC, Zhao WZ, Huang HJ, Lo YL, Wang HT, Lin AMY. Sci Rep. 2017 Apr 12;7:45741.
6Enhancing Anticancer Effect of Gefitinib across the Blood-Brain Barrier Model Using Liposomes Modified with One α-Helical Cell-Penetrating Peptide or Glutathione and Tween 80. Lin KH, Hong ST, Wang HT, Lo YL, Lin AMY, Yang JC. Int J Mol Sci. 2016 Nov 29;17(12).
7Acrolein induces mtDNA damages, mitochondrial fission and mitophagy in human lung cells.Wang HT, Lin JH, Yang CH, Haung CH, Weng CW, Lin AMY., Lo YL, Chen WS, Tang MS.Oncotarget. 2017 Jul 31;8(41):70406-70421.
8Baicalein attenuates α-synuclein aggregation, inflammasome activation and autophagy in the MPP+-treated nigrostriataldopaminergic system in vivo. Hung KC, Huang HJ, Wang YT, Lin AMY. J Ethnopharmacol. 2016 Dec 24;194:522-529.
9Melatonin Ameliorates Arsenite-Induced Neurotoxicity: Involvement of Autophagy and Mitochondria. Teng YC, Tai YI, Huang HJ, Lin AMY. Mol Neurobiol. 2015 Oct;52(2):1015-22.
10Role of autophagy in arsenite-induced neurotoxicity: the involvement of α-synuclein. Teng YC, Jeng CJ, Huang HJ, Lin AMY. Toxicol Lett. 2015 Jan 29;233(3):239-245.
11Chloroquine enhances gefitinib cytotoxicity in gefitinib-resistant nonsmall cell lung cancer cells. Tang MC, Wu MY, Hwang MH, Chang YT, Huang HJ, Lin AMY. Yang JCH. PLoS One.2015 Mar 25;10(3)
12
Roles of autophagy in MPP+-induced neurotoxicity in vivo: the involvement of mitochondria and α-synuclein aggregation. Hung KC, Huang HJ, Lin MW, Lei YP, Lin AMY. PLoS One. 2014 Mar 19;9(3):e91074.

五年內執行計畫

實驗室成員

職稱/學位姓名
研究助理
博士後研究員
博士班
碩士班
畢業生(博)
畢業生(碩)賴錦輝、董緗雯、王證豪、陳玟翰、李怡芬、趙珮珊、周宥樺、張志鋒、余惠真、曾雅瑋、戴佑易、洪楷智、鄧郁君、廖丹瑋、黃保碩、王怡婷